Assistant Project Scientist – Activity-dependent Translational Control - Ingolia Lab – Molecular and Cell Biology
Position overview
Position title: Assistant Project ScientistApplication Window
Open date: November 10, 2024
Next review date: Sunday, Nov 24, 2024 at 11:59pm (Pacific Time)
Apply by this date to ensure full consideration by the committee.
Final date: Tuesday, Dec 10, 2024 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.
Position description
The Department of Molecular and Cellular Biology at the University of California, Berkeley seeks applications for an Assistant Project Scientist in the Ingolia Lab, in the area of activity-dependent control of translation in neurons.
The Ingolia lab studies the molecular mechanisms of post-transcriptional gene regulation and the cellular and organismal roles of regulated protein synthesis. Regulated translation in neurons is important for potentiation and homeostasis; defects in neuronal translational control are associated with neurodevelopmental and neurodegenerative disorders. This project seeks to map the regulated translational programs associated with neuronal activity using new tools we have developed for this purpose.
The duties of the position include:
• Conducing molecular biology and genomics experiments in cultured primary mouse neurons
• Neuroscience experiments in mice, including viral delivery of expression constructs
• Analysis of mouse brain samples, including fluorescence microscopy and expansion microscopy
• RNA-seq and ribosome profiling library construction and sequencing
• Designing, executing, and troubleshooting experiments in molecular neuroscience
• Computational and statistical analysis of high-throughput sequencing data
• Attending scientific seminars, meetings, and workshops and presenting research findings
• Pursuing publication of research in peer-reviewed journals
• Developing and maintaining collaborative research relationships
• Pursuing funding opportunities consistent with the research program
• Planning and developing new research directions related to current work
• Training and mentoring lab members
This position provides full benefits.
Qualifications
PhD (or equivalent international degree)
Ph.D. in Cellular and Molecular Physiology, Neuroscience, or related field.
Experience with high-throughput sequencing, RNA sequencing, and ribosome profiling
Experience with proximity-dependent protein labeling
Experience with calcium-dependent activity reporters
Experience with calcium-dependent protein labeling technologies
Experience with neuronal culture
Experience with mouse husbandry and neurobiology
Ability to develop and troubleshoot new methods and techniques
Ability to identify and pursue exciting questions in cellular and molecular neurobiology
Outstanding writing and communication skills
Strong publication record in peer-reviewed journal
Ability and desire to contribute to advancing diversity, equity, inclusion, and belonging.
Application Requirements
Curriculum Vitae - Your most recently updated C.V.
Cover Letter
Statement of Research
Statement on Contributions to Diversity, Equity, Inclusion, and Belonging - Statement on your contributions to diversity, equity, inclusion, and belonging in research, teaching, and service, including information about your record of activities to date, and plans for contributing if hired at UC Berkeley. More Information and guidelines.
(Optional)
- 3-5 required (contact information only)
Help contact: ingolia@berkeley.edu
About UC Berkeley
UC Berkeley is committed to diversity, equity, inclusion, and belonging. The excellence of the institution requires an environment in which the diverse community of faculty, students, and staff are welcome and included. Successful candidates will demonstrate knowledge and skill related to ensuring equity and inclusion in the activities of their academic position (e.g., teaching, research, and service, as applicable).
The University of California, Berkeley is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status.
Please refer to the University of California’s Affirmative Action Policy and the University of California’s Anti-Discrimination Policy.
In searches when letters of reference are required all letters will be treated as confidential per University of California policy and California state law. Please refer potential referees, including when letters are provided via a third party (i.e., dossier service or career center), to the UC Berkeley statement of confidentiality prior to submitting their letter.
As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.