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Assistant Project Scientist - Bioengineering - Clark Lab

Position overview

Salary range: Commensurate with experience
Percent time: 100%
Anticipated start: February 1, 2022
Position duration: 1 year

Application Window

Open date: December 9, 2021

Next review date: Wednesday, Dec 7, 2022 at 11:59pm (Pacific Time)
Apply by this date to ensure full consideration by the committee.

Final date: Thursday, Dec 8, 2022 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.

Position description

This position is in the Clark lab, within the Department of Bioengineering - California Institute for Quantitative Biosciences at the University of California Berkeley. The Clark Lab develops microfluidic and molecular methods for the high throughput analysis of single cells. We use these techniques to study HIV latency in CD4 T cells and profile cellular interactions during central nervous system inflammation.

The Clark lab seeks a talented and driven scientist to lead droplet-based high-throughput forward genetic screens. Central nervous system (CNS)-resident astrocytes and microglia interact to regulate pro-inflammatory programs that drive neurodegenerative diseases, but the pathways and molecules involved are largely unknown. Understanding the language of inflammation is a central question in the field of Neuroimmunology and may guide new therapeutic approaches for neurologic diseases. To address this challenge, the candidate will conduct in vivo and in vitro CRISPR screens to understand the genes, pathway, and molecules involved in neuroinflammation. This is part of our larger effort to build and deploy novel methods to study the interactions between CNS-resident cells. The candidate is expected to collect, analyze, and publish their results in peer review scientific journals, assist in the writing of proposals for funding from federal agencies and other organizations, and present findings at scientific conferences. The ideal candidate is an effective communicator, is open to collaboration, and enjoys engaging with a diverse community of academic researchers.


Basic qualifications (required at time of application)

Ph.D. or equivalent international degree.

Additional qualifications (required at time of start)

• A minimum of 3 years of post-doctoral research experience.

Preferred qualifications

• PhD degree in bioengineering or a related field such as molecular biology, immunology, or neurology
• Experience with genetic manipulation of mammalian cells.
• Experience with CRISPR screening methods
• Experience with Fluorescence activated cell sorting
• Experience with models of neuroinflammation and/ or neurologic diseases
• Experience with NGS library prep and Illumina sequencing
• Experience with Confocal microscopy
• Experience with Droplet microfluidics
• At least 3 first-authored peer reviewed publications

Application Requirements

Document requirements
  • Curriculum Vitae - Your most recently updated C.V.

  • Cover Letter

  • Statement of Research (Optional)

Reference requirements
  • 3-5 required (contact information only)
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Campus Information

Diversity, equity, inclusion, and belonging are core values at UC Berkeley. Our excellence can only be fully realized by faculty, students, and academic and non-academic staff who share our commitment to these values. Successful candidates for our academic positions will demonstrate evidence of a commitment to advancing equity, inclusion, and belonging.

The University of California, Berkeley is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy see:

In searches when letters of reference are required all letters will be treated as confidential per University of California policy and California state law. Please refer potential referees, including when letters are provided via a third party (i.e., dossier service or career center), to the UC Berkeley statement of confidentiality ( prior to submitting their letter.

As a condition of employment, you will be required to comply with the University of California SARS-CoV-2 (COVID-19) Vaccination Program Policy. All Covered Individuals under the policy must provide proof of Full Vaccination or, if applicable, submit a request for Exception (based on Medical Exemption, Disability, and/or Religious Objection) or Deferral (based on pregnancy) no later than the applicable deadline. Please refer to Appendix F, Section II.C. of the policy for the deadlines applicable to new University of California employees. (Capitalized terms in this paragraph are defined in the policy.) Federal, state, or local public health directives may impose additional requirements.

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Job location

Berkeley, CA